Changes in the expression of the potassium channels TASK1, TASK3 and TRESK in a rat model of oral squamous cell carcinoma and their relation to malignancy

•4-NQO induced rat OSCC expresses the K2 P channels TASK1, TASK3 and TRESK.•OSCC has decreased TASK1 and TRESK and increased TASK3 expression.•OSCC expresses high levels of the malignancy and taxane-resistance marker β-tubulin 3.•TASK3 and TRESK but not TASK1 correlate positively with β-tubulin 3 in...

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Veröffentlicht in:	Archives of oral biology 2019-04, Vol.100, p.75-85
Hauptverfasser:	Zavala, Walther D., Foscolo, Mabel R., Kunda, Patricia E., Cavicchia, Juan C., Acosta, Cristian G.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-nitroquinoline-1-oxide Animals Beta tubulin 3 Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Dentistry Down-Regulation Humans K2P channels Male Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Nerve Tissue Proteins Oral cancer Potassium channel Potassium Channels - metabolism Potassium Channels, Tandem Pore Domain - metabolism Rats Tubulin - metabolism
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