Regulation of extracellular ATP of human erythrocytes treated with α-hemolysin. Effects of cell volume, morphology, rheology and hemolysis

Alpha-hemolysin (HlyA) of uropathogenic strains of Escherichia coli irreversibly binds to human erythrocytes (RBCs) and triggers activation of ATP release and metabolic changes ultimately leading to hemolysis. We studied the regulation of extracellular ATP (ATPe) of RBCs exposed to HlyA. Luminometry...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2019-05, Vol.1866 (5), p.896-915
Hauptverfasser:	Leal Denis, M.F., Lefevre, S.D., Alvarez, C.L., Lauri, N., Enrique, N., Rinaldi, D.E., Gonzalez-Lebrero, R., Vecchio, L.E., Espelt, M.V., Stringa, P., Muñoz-Garay, C., Milesi, V., Ostuni, M.A., Herlax, V., Schwarzbaum, P.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion, aggregation ATP-transport E.coli hemolysin Hemolysis
Online-Zugang:	Volltext
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