HMGA2 and Bach‐1 cooperate to promote breast cancer cell malignancy

During breast cancer progression, tumor cells acquire multiple malignant features. The transcription factors and cell cycle regulators high mobility group A2 (HMGA2) and BTB and CNC homology 1 (Bach‐1) are overexpressed in several cancers, but the mechanistic understanding of how HMGA2 and Bach‐1 pr...

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Veröffentlicht in:	Journal of cellular physiology 2019-10, Vol.234 (10), p.17714-17726
Hauptverfasser:	Mansoori, Behzad, Mohammadi, Ali, Asadzadeh, Zahra, Shirjang, Solmaz, Minouei, Mahsa, Abedi Gaballu, Fereydoon, Shajari, Neda, Kazemi, Tohid, Gjerstorff, Morten F., Duijf, Pascal H.G., Baradaran, Behzad
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - genetics bach1 Basic-Leucine Zipper Transcription Factors - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology cancer stem cell Caspase Cell cycle Cell death Cell Line, Tumor Cell migration Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Disease Progression Down-Regulation - genetics EMT Epithelial-Mesenchymal Transition - genetics Female Gene Expression Regulation, Neoplastic - genetics High mobility group proteins HMGA2 HMGA2 Protein - genetics Homology Humans Malignancy Mesenchyme Middle Aged Numerical controls Proteins Regulators Transcription factors Tumor cells Tumors Up-Regulation - genetics
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