Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style
•No significant between-group differences were observed in this study for frequencies of FTO alleles.•FTO genotype interacted with attachment style to predict binge frequency.•rs1421085 interacts with insecure attachment in a way that may exacerbate binge eating. The genetics of binge-eating disorde...
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| Veröffentlicht in: | Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2019-05, Vol.61, p.208-212 |
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| creator | Cameron, Jameason D. Tasca, Giorgio A. Little, Julian Chyurlia, Livia Ritchie, Kerri Yeh, Ed Doucette, Steve Obregon, Ana-Maria Bulman, Dennis E. Doucet, Éric Goldfield, Gary S. |
| description | •No significant between-group differences were observed in this study for frequencies of FTO alleles.•FTO genotype interacted with attachment style to predict binge frequency.•rs1421085 interacts with insecure attachment in a way that may exacerbate binge eating.
The genetics of binge-eating disorder (BED) is an emerging topic and one candidate pathway, namely the fat mass and obesity-associated (FTO) gene, may be implicated because of its role in food reward sensitivity and self-regulation of eating. The aims of this study were to examine the independent effects of variants of FTO on binge frequency in women with and without BED and to examine the moderating role of interpersonal attachment in this association.
Secondary data analysis was conducted on a cross-sectional comparison of three groups of women in a trial of group treatment for BED: BED with obesity (n = 73), BED without obesity (n = 55), and normal weight without BED (n = 50). Women were genotyped for five of the most common FTO single-nucleotide polymorphisms, rs9939609, rs8050136, rs3751812, rs1421085, and rs1121980, which have been related to body mass index and energy intake. Binge frequency (Eating Disorder Examination), body composition (bioelectric impedance), and attachment (Attachment Style Questionnaire) were assessed.
There were no significant between-group differences for frequencies of FTO alleles, nor were there any significant anthropometric associations. The FTO × attachment interaction was significant whereby, relative to a low-risk FTO genotype, individuals with a high-risk genotype for the SNP rs1421085 and high-avoidant attachment had higher mean binge frequency than those with high genetic risk but low-avoidant attachment (β = –7.96; t = –2.07; P = 0.042).
FTO genotypes associated with risk for obesity and loss of control of eating, specifically rs1421085, may interact with insecure attachment in a way that may exacerbate binge eating among women with BED. |
| doi_str_mv | 10.1016/j.nut.2018.11.006 |
| format | Article |
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The genetics of binge-eating disorder (BED) is an emerging topic and one candidate pathway, namely the fat mass and obesity-associated (FTO) gene, may be implicated because of its role in food reward sensitivity and self-regulation of eating. The aims of this study were to examine the independent effects of variants of FTO on binge frequency in women with and without BED and to examine the moderating role of interpersonal attachment in this association.
Secondary data analysis was conducted on a cross-sectional comparison of three groups of women in a trial of group treatment for BED: BED with obesity (n = 73), BED without obesity (n = 55), and normal weight without BED (n = 50). Women were genotyped for five of the most common FTO single-nucleotide polymorphisms, rs9939609, rs8050136, rs3751812, rs1421085, and rs1121980, which have been related to body mass index and energy intake. Binge frequency (Eating Disorder Examination), body composition (bioelectric impedance), and attachment (Attachment Style Questionnaire) were assessed.
There were no significant between-group differences for frequencies of FTO alleles, nor were there any significant anthropometric associations. The FTO × attachment interaction was significant whereby, relative to a low-risk FTO genotype, individuals with a high-risk genotype for the SNP rs1421085 and high-avoidant attachment had higher mean binge frequency than those with high genetic risk but low-avoidant attachment (β = –7.96; t = –2.07; P = 0.042).
FTO genotypes associated with risk for obesity and loss of control of eating, specifically rs1421085, may interact with insecure attachment in a way that may exacerbate binge eating among women with BED.</description><identifier>ISSN: 0899-9007</identifier><identifier>EISSN: 1873-1244</identifier><identifier>DOI: 10.1016/j.nut.2018.11.006</identifier><identifier>PMID: 30822753</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Age ; Alleles ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics ; Anthropometry ; Attachment ; Automatic control ; BED ; Binge eating ; Binge-Eating Disorder - genetics ; Binge-Eating Disorder - psychology ; Bioelectricity ; Body Composition ; Body fat ; Body Mass Index ; Body size ; Bulimia - genetics ; Bulimia - psychology ; Clinical Trials as Topic ; Cross-Sectional Studies ; Data analysis ; Data processing ; Eating ; Eating behavior ; Eating disorders ; Electric Impedance ; Emotions ; Energy intake ; Female ; FTO ; Gene frequency ; Genetics ; Genotype ; Genotype & phenotype ; Genotypes ; Humans ; Ideal Body Weight ; Middle Aged ; Obesity ; Obesity - genetics ; Obesity - psychology ; Object Attachment ; Polymorphism, Single Nucleotide ; Reinforcement ; Risk ; Single-nucleotide polymorphism ; Weight ; Weight control ; Womens health</subject><ispartof>Nutrition (Burbank, Los Angeles County, Calif.), 2019-05, Vol.61, p.208-212</ispartof><rights>2018</rights><rights>Copyright © 2018. Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited May 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-4e358db63dd95b75d7fd50826829721bcd6373c400af46dcaa03e73969aaccd73</citedby><cites>FETCH-LOGICAL-c381t-4e358db63dd95b75d7fd50826829721bcd6373c400af46dcaa03e73969aaccd73</cites><orcidid>0000-0001-7591-6935 ; 0000-0001-6216-7824</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2191338033?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30822753$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cameron, Jameason D.</creatorcontrib><creatorcontrib>Tasca, Giorgio A.</creatorcontrib><creatorcontrib>Little, Julian</creatorcontrib><creatorcontrib>Chyurlia, Livia</creatorcontrib><creatorcontrib>Ritchie, Kerri</creatorcontrib><creatorcontrib>Yeh, Ed</creatorcontrib><creatorcontrib>Doucette, Steve</creatorcontrib><creatorcontrib>Obregon, Ana-Maria</creatorcontrib><creatorcontrib>Bulman, Dennis E.</creatorcontrib><creatorcontrib>Doucet, Éric</creatorcontrib><creatorcontrib>Goldfield, Gary S.</creatorcontrib><title>Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style</title><title>Nutrition (Burbank, Los Angeles County, Calif.)</title><addtitle>Nutrition</addtitle><description>•No significant between-group differences were observed in this study for frequencies of FTO alleles.•FTO genotype interacted with attachment style to predict binge frequency.•rs1421085 interacts with insecure attachment in a way that may exacerbate binge eating.
The genetics of binge-eating disorder (BED) is an emerging topic and one candidate pathway, namely the fat mass and obesity-associated (FTO) gene, may be implicated because of its role in food reward sensitivity and self-regulation of eating. The aims of this study were to examine the independent effects of variants of FTO on binge frequency in women with and without BED and to examine the moderating role of interpersonal attachment in this association.
Secondary data analysis was conducted on a cross-sectional comparison of three groups of women in a trial of group treatment for BED: BED with obesity (n = 73), BED without obesity (n = 55), and normal weight without BED (n = 50). Women were genotyped for five of the most common FTO single-nucleotide polymorphisms, rs9939609, rs8050136, rs3751812, rs1421085, and rs1121980, which have been related to body mass index and energy intake. Binge frequency (Eating Disorder Examination), body composition (bioelectric impedance), and attachment (Attachment Style Questionnaire) were assessed.
There were no significant between-group differences for frequencies of FTO alleles, nor were there any significant anthropometric associations. The FTO × attachment interaction was significant whereby, relative to a low-risk FTO genotype, individuals with a high-risk genotype for the SNP rs1421085 and high-avoidant attachment had higher mean binge frequency than those with high genetic risk but low-avoidant attachment (β = –7.96; t = –2.07; P = 0.042).
FTO genotypes associated with risk for obesity and loss of control of eating, specifically rs1421085, may interact with insecure attachment in a way that may exacerbate binge eating among women with BED.</description><subject>Adult</subject><subject>Age</subject><subject>Alleles</subject><subject>Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics</subject><subject>Anthropometry</subject><subject>Attachment</subject><subject>Automatic control</subject><subject>BED</subject><subject>Binge eating</subject><subject>Binge-Eating Disorder - genetics</subject><subject>Binge-Eating Disorder - psychology</subject><subject>Bioelectricity</subject><subject>Body Composition</subject><subject>Body fat</subject><subject>Body Mass Index</subject><subject>Body size</subject><subject>Bulimia - genetics</subject><subject>Bulimia - psychology</subject><subject>Clinical Trials as Topic</subject><subject>Cross-Sectional Studies</subject><subject>Data analysis</subject><subject>Data processing</subject><subject>Eating</subject><subject>Eating behavior</subject><subject>Eating disorders</subject><subject>Electric Impedance</subject><subject>Emotions</subject><subject>Energy intake</subject><subject>Female</subject><subject>FTO</subject><subject>Gene frequency</subject><subject>Genetics</subject><subject>Genotype</subject><subject>Genotype & phenotype</subject><subject>Genotypes</subject><subject>Humans</subject><subject>Ideal Body Weight</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - genetics</subject><subject>Obesity - psychology</subject><subject>Object Attachment</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Reinforcement</subject><subject>Risk</subject><subject>Single-nucleotide polymorphism</subject><subject>Weight</subject><subject>Weight control</subject><subject>Womens health</subject><issn>0899-9007</issn><issn>1873-1244</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kcFu1DAQhi1ERZfCA3BBlriUQ1I7TuIETqhqaaVKvSxny7EnXa8Se7Gdon0g3pNZ7ZYDBy4eW_PNr_H_E_KBs5Iz3l5tS7_ksmK8KzkvGWtfkRXvpCh4VdevyYp1fV_0jMlz8jalLWOM923_hpwL1lWVbMSK_L4ZRzA50TDSUWc665So9paGAZLL-wLfwTidwdLL2_XjZ_oEHuguTPs5xN3GpRlnPR2cfwIKOmOlztNfYQY8Xd4cW8WpZV0K0UL8QtcboHPA68vMOC3gDRw20Tlrs0GFTFPeT_COnI16SvD-VC_Ij9ub9fVd8fD4_f7620NhRMdzUYNoOju0wtq-GWRj5Wgb_GrbVb2s-GBsK6QwNWN6rFtrtGYCpEBPtDbGSnFBLo-6uxh-LpCyml0yME3aQ1iSqtDdpqpFUyP66R90G5bocTukei5Ex4RAih8pE0NKEUa1i27Wca84U4cM1VZhhuqQoeJcYYY48_GkvAwz2L8TL6Eh8PUIAFrx7CCqZNzBOusiZqlscP-R_wOS0K65</recordid><startdate>201905</startdate><enddate>201905</enddate><creator>Cameron, Jameason D.</creator><creator>Tasca, Giorgio A.</creator><creator>Little, Julian</creator><creator>Chyurlia, Livia</creator><creator>Ritchie, Kerri</creator><creator>Yeh, Ed</creator><creator>Doucette, Steve</creator><creator>Obregon, Ana-Maria</creator><creator>Bulman, Dennis E.</creator><creator>Doucet, Éric</creator><creator>Goldfield, Gary S.</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7591-6935</orcidid><orcidid>https://orcid.org/0000-0001-6216-7824</orcidid></search><sort><creationdate>201905</creationdate><title>Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style</title><author>Cameron, Jameason D. ; Tasca, Giorgio A. ; Little, Julian ; Chyurlia, Livia ; Ritchie, Kerri ; Yeh, Ed ; Doucette, Steve ; Obregon, Ana-Maria ; Bulman, Dennis E. ; Doucet, Éric ; Goldfield, Gary S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-4e358db63dd95b75d7fd50826829721bcd6373c400af46dcaa03e73969aaccd73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Age</topic><topic>Alleles</topic><topic>Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics</topic><topic>Anthropometry</topic><topic>Attachment</topic><topic>Automatic control</topic><topic>BED</topic><topic>Binge eating</topic><topic>Binge-Eating Disorder - genetics</topic><topic>Binge-Eating Disorder - psychology</topic><topic>Bioelectricity</topic><topic>Body Composition</topic><topic>Body fat</topic><topic>Body Mass Index</topic><topic>Body size</topic><topic>Bulimia - genetics</topic><topic>Bulimia - psychology</topic><topic>Clinical Trials as Topic</topic><topic>Cross-Sectional Studies</topic><topic>Data analysis</topic><topic>Data processing</topic><topic>Eating</topic><topic>Eating behavior</topic><topic>Eating disorders</topic><topic>Electric Impedance</topic><topic>Emotions</topic><topic>Energy intake</topic><topic>Female</topic><topic>FTO</topic><topic>Gene frequency</topic><topic>Genetics</topic><topic>Genotype</topic><topic>Genotype & phenotype</topic><topic>Genotypes</topic><topic>Humans</topic><topic>Ideal Body Weight</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity - genetics</topic><topic>Obesity - psychology</topic><topic>Object Attachment</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Reinforcement</topic><topic>Risk</topic><topic>Single-nucleotide polymorphism</topic><topic>Weight</topic><topic>Weight control</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cameron, Jameason D.</creatorcontrib><creatorcontrib>Tasca, Giorgio A.</creatorcontrib><creatorcontrib>Little, Julian</creatorcontrib><creatorcontrib>Chyurlia, Livia</creatorcontrib><creatorcontrib>Ritchie, Kerri</creatorcontrib><creatorcontrib>Yeh, Ed</creatorcontrib><creatorcontrib>Doucette, Steve</creatorcontrib><creatorcontrib>Obregon, Ana-Maria</creatorcontrib><creatorcontrib>Bulman, Dennis E.</creatorcontrib><creatorcontrib>Doucet, Éric</creatorcontrib><creatorcontrib>Goldfield, Gary S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Career & Technical Education Database</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Nutrition (Burbank, Los Angeles County, Calif.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cameron, Jameason D.</au><au>Tasca, Giorgio A.</au><au>Little, Julian</au><au>Chyurlia, Livia</au><au>Ritchie, Kerri</au><au>Yeh, Ed</au><au>Doucette, Steve</au><au>Obregon, Ana-Maria</au><au>Bulman, Dennis E.</au><au>Doucet, Éric</au><au>Goldfield, Gary S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style</atitle><jtitle>Nutrition (Burbank, Los Angeles County, Calif.)</jtitle><addtitle>Nutrition</addtitle><date>2019-05</date><risdate>2019</risdate><volume>61</volume><spage>208</spage><epage>212</epage><pages>208-212</pages><issn>0899-9007</issn><eissn>1873-1244</eissn><abstract>•No significant between-group differences were observed in this study for frequencies of FTO alleles.•FTO genotype interacted with attachment style to predict binge frequency.•rs1421085 interacts with insecure attachment in a way that may exacerbate binge eating.
The genetics of binge-eating disorder (BED) is an emerging topic and one candidate pathway, namely the fat mass and obesity-associated (FTO) gene, may be implicated because of its role in food reward sensitivity and self-regulation of eating. The aims of this study were to examine the independent effects of variants of FTO on binge frequency in women with and without BED and to examine the moderating role of interpersonal attachment in this association.
Secondary data analysis was conducted on a cross-sectional comparison of three groups of women in a trial of group treatment for BED: BED with obesity (n = 73), BED without obesity (n = 55), and normal weight without BED (n = 50). Women were genotyped for five of the most common FTO single-nucleotide polymorphisms, rs9939609, rs8050136, rs3751812, rs1421085, and rs1121980, which have been related to body mass index and energy intake. Binge frequency (Eating Disorder Examination), body composition (bioelectric impedance), and attachment (Attachment Style Questionnaire) were assessed.
There were no significant between-group differences for frequencies of FTO alleles, nor were there any significant anthropometric associations. The FTO × attachment interaction was significant whereby, relative to a low-risk FTO genotype, individuals with a high-risk genotype for the SNP rs1421085 and high-avoidant attachment had higher mean binge frequency than those with high genetic risk but low-avoidant attachment (β = –7.96; t = –2.07; P = 0.042).
FTO genotypes associated with risk for obesity and loss of control of eating, specifically rs1421085, may interact with insecure attachment in a way that may exacerbate binge eating among women with BED.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30822753</pmid><doi>10.1016/j.nut.2018.11.006</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0001-7591-6935</orcidid><orcidid>https://orcid.org/0000-0001-6216-7824</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0899-9007 |
| ispartof | Nutrition (Burbank, Los Angeles County, Calif.), 2019-05, Vol.61, p.208-212 |
| issn | 0899-9007 1873-1244 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2187524354 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Adult Age Alleles Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics Anthropometry Attachment Automatic control BED Binge eating Binge-Eating Disorder - genetics Binge-Eating Disorder - psychology Bioelectricity Body Composition Body fat Body Mass Index Body size Bulimia - genetics Bulimia - psychology Clinical Trials as Topic Cross-Sectional Studies Data analysis Data processing Eating Eating behavior Eating disorders Electric Impedance Emotions Energy intake Female FTO Gene frequency Genetics Genotype Genotype & phenotype Genotypes Humans Ideal Body Weight Middle Aged Obesity Obesity - genetics Obesity - psychology Object Attachment Polymorphism, Single Nucleotide Reinforcement Risk Single-nucleotide polymorphism Weight Weight control Womens health |
| title | Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T19%3A58%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20fat%20mass%20and%20obesity-associated%20(FTO)%20gene%20polymorphisms%20on%20binge%20eating%20in%20women%20with%20binge-eating%20disorder:%20The%20moderating%20influence%20of%20attachment%20style&rft.jtitle=Nutrition%20(Burbank,%20Los%20Angeles%20County,%20Calif.)&rft.au=Cameron,%20Jameason%20D.&rft.date=2019-05&rft.volume=61&rft.spage=208&rft.epage=212&rft.pages=208-212&rft.issn=0899-9007&rft.eissn=1873-1244&rft_id=info:doi/10.1016/j.nut.2018.11.006&rft_dat=%3Cproquest_cross%3E2191338033%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2191338033&rft_id=info:pmid/30822753&rft_els_id=S0899900718305021&rfr_iscdi=true |