MCAM abnormal expression and clinical outcome associations are highly cancer dependent as revealed through pan-cancer analysis

Abstract MCAM (CD146) is a cell surface adhesion molecule that has been reported to promote cancer development, progression and metastasis and is considered as a potential tumor biomarker and therapeutic target. However, inconsistent reports exist, and its clinical value is yet to be confirmed. Here...

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Veröffentlicht in:	Briefings in bioinformatics 2020-03, Vol.21 (2), p.709-718
Hauptverfasser:	An, Yunxia, Wei, Nan, Cheng, Xiangsong, Li, Ying, Liu, Haiyang, Wang, Jia, Xu, Zhiwei, Sun, Zhifu, Zhang, Xiaoju
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biotechnology Blood vessels Cancer Cell surface Clinical outcomes Data collection Drug development Encyclopedias Gene expression Genomes Genotypes Metastases Phenotypes Therapeutic applications Tissues Tumor cell lines Tumors
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