Upregulated tissue expression of T helper (Th) 17 pathogenic interleukin (IL)-23 and IL-1β in Hashimoto’s thyroiditis but not in Graves’ disease

T helper (Th) 17 cells and interleukin (IL)-17 play a significant role in the pathogenesis of autoimmune thyroid disease (AITD). However, it has recently become clear that Th17 cells are more heterogeneous and exhibit two different phenotypes, whereas IL-23 and IL-1β are crucial for the generation o...

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Veröffentlicht in:Endocrine Journal 2019, Vol.66(5), pp.423-430
Hauptverfasser: Zake, Tatjana, Skuja, Sandra, Kalere, Ieva, Konrade, Ilze, Groma, Valerija
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Sprache:eng
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