Phosphine‐Catalyzed (3+2) Annulation of Isoindigos with Allenes: Enantioselective Formation of Two Vicinal Quaternary Stereogenic Centers

Construction of contiguous all‐carbon quaternary stereogenic centers is a long‐standing challenge in synthetic organic chemistry. In this report, a phosphine‐catalyzed enantioselective (3+2) annulation reaction between allenes and isoindigos, containing either two identical or different oxindole moi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2019-05, Vol.58 (19), p.6260-6264
Hauptverfasser:	Chan, Wai‐Lun, Tang, Xiaodong, Zhang, Fuhao, Quek, Glenn, Mei, Guang‐Jian, Lu, Yixin
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaloids allenes annulations Chemical reactions Construction Enantiomers Natural products Organic chemistry organocatalysis Phosphine spiro compounds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!