Natural history, pathophysiology and evaluation of gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) is one of the most common diseases encountered by both internists and gastroenterologists. GERD can cause a wide variety of symptoms ranging from heartburn and regurgitation to more atypical symptoms such as cough, chest pain, and hoarseness. The diagnosis is o...
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| Veröffentlicht in: | Disease-a-month 2020-01, Vol.66 (1), p.100848-100848, Article 100848 |
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| container_title | Disease-a-month |
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| creator | Chatila, Ahmed T. Nguyen, Minh Thu T. Krill, Timothy Roark, Russell Bilal, Mohammad Reep, Gabriel |
| description | Gastroesophageal reflux disease (GERD) is one of the most common diseases encountered by both internists and gastroenterologists. GERD can cause a wide variety of symptoms ranging from heartburn and regurgitation to more atypical symptoms such as cough, chest pain, and hoarseness. The diagnosis is often times made on the basis of history and clinical symptomatology. The prevalence of GERD is currently estimated to be 8–33% with the incidence of disease only expected to increase over time. Although most cases of GERD can be diagnosed based on symptoms and clinical presentation, the diagnosis of GERD can be challenging when symptoms are atypical. In this review, we provide a comprehensive summary of the epidemiology, pathophysiology, evaluation and diagnosis of gastroesophageal reflux disease. |
| doi_str_mv | 10.1016/j.disamonth.2019.02.001 |
| format | Article |
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GERD can cause a wide variety of symptoms ranging from heartburn and regurgitation to more atypical symptoms such as cough, chest pain, and hoarseness. The diagnosis is often times made on the basis of history and clinical symptomatology. The prevalence of GERD is currently estimated to be 8–33% with the incidence of disease only expected to increase over time. Although most cases of GERD can be diagnosed based on symptoms and clinical presentation, the diagnosis of GERD can be challenging when symptoms are atypical. 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In this review, we provide a comprehensive summary of the epidemiology, pathophysiology, evaluation and diagnosis of gastroesophageal reflux disease.</description><subject>Asthma - etiology</subject><subject>Barium Sulfate</subject><subject>Contrast Media</subject><subject>Cough - etiology</subject><subject>Drug-Related Side Effects and Adverse Reactions</subject><subject>Endoscopy, Digestive System</subject><subject>Esophageal pH Monitoring</subject><subject>Evaluation</subject><subject>Female</subject><subject>Food - adverse effects</subject><subject>Gastroesophageal Reflux - diagnosis</subject><subject>Gastroesophageal Reflux - physiopathology</subject><subject>Gastroesophageal reflux disease</subject><subject>Genetic Predisposition to Disease</subject><subject>GERD</subject><subject>Heart burn</subject><subject>Hernia, Hiatal - complications</subject><subject>Humans</subject><subject>Laryngitis - etiology</subject><subject>Manometry</subject><subject>Obesity - complications</subject><subject>Pregnancy</subject><subject>Pregnancy Complications</subject><subject>Proton Pump Inhibitors</subject><subject>Risk Factors</subject><subject>Smoking</subject><issn>0011-5029</issn><issn>1557-8194</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1PwyAUhonRuDn9C9pLL2wF-gG9XIxfyaKJ0WtC6enK0pUJdLH_XpbN3XpFIM_Lec-D0A3BCcGkuF8ltXZybXrfJhSTMsE0wZicoCnJcxZzUmanaBpeSJxjWk7QhXOrcKVljs_RJMUcp4zmU_TxJv1gZRe12nljx7toI31rNu3otOnMcoxkX0ewld0gvTZ9ZJpoKZ23Blyg5BJC1kLTDT9RqATSwSU6a2Tn4OpwztDX0-Pnw0u8eH9-fZgvYpUy4mOgVcNrqNJQhVc85QozxhSRTcYKJlVGK5w3nPG0IRQKIDSDDNKyUjnOWUPTGbrd_7ux5nsA58VaOwVdJ3swgxOU8IJkRYGzgLI9qqxxLtQVG6vX0o6CYLETKlbiKFTshApMRfAVkteHIUO1hvqY-zMYgPkegLDqVoMVTmnoFdTagvKiNvrfIb-ZIoy3</recordid><startdate>202001</startdate><enddate>202001</enddate><creator>Chatila, Ahmed T.</creator><creator>Nguyen, Minh Thu T.</creator><creator>Krill, Timothy</creator><creator>Roark, Russell</creator><creator>Bilal, Mohammad</creator><creator>Reep, Gabriel</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202001</creationdate><title>Natural history, pathophysiology and evaluation of gastroesophageal reflux disease</title><author>Chatila, Ahmed T. ; 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| fulltext | fulltext |
| identifier | ISSN: 0011-5029 |
| ispartof | Disease-a-month, 2020-01, Vol.66 (1), p.100848-100848, Article 100848 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Asthma - etiology Barium Sulfate Contrast Media Cough - etiology Drug-Related Side Effects and Adverse Reactions Endoscopy, Digestive System Esophageal pH Monitoring Evaluation Female Food - adverse effects Gastroesophageal Reflux - diagnosis Gastroesophageal Reflux - physiopathology Gastroesophageal reflux disease Genetic Predisposition to Disease GERD Heart burn Hernia, Hiatal - complications Humans Laryngitis - etiology Manometry Obesity - complications Pregnancy Pregnancy Complications Proton Pump Inhibitors Risk Factors Smoking |
| title | Natural history, pathophysiology and evaluation of gastroesophageal reflux disease |
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