Imaging and Characterization of Macrophage Distribution in Mouse Models of Human Prostate Cancer

Purpose Prostate carcinoma consists of tumor epithelium and malignant stroma. Until recently, diagnostic and therapeutic efforts have focused exclusively on targeting characteristics of the tumor epithelium, ignoring opportunities to target inflammatory infiltrate and extracellular matrix components...

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Veröffentlicht in:	Molecular imaging and biology 2019-12, Vol.21 (6), p.1054-1063
Hauptverfasser:	Copeland, Ben T., Shallal, Hassan, Shen, Chentian, Pienta, Kenneth J., Foss, Catherine A., Pomper, Martin G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - chemistry Acetamides - metabolism Androgen receptors Animal models Animals Antigens Benzenesulfonates - chemistry Benzenesulfonates - metabolism Cancer Cell Line, Tumor Cell Proliferation Cytotoxicity Diagnostic Imaging Diagnostic systems Disease Models, Animal Epithelium Epithelium - pathology Extracellular matrix Fluorescence Genotype & phenotype Humans Imaging Indoles - chemistry Indoles - metabolism Inflammation Infrared imaging Macrophages Macrophages - pathology Male Medical imaging Medical prognosis Medicine Medicine & Public Health Mice Mice, Nude Phenotype Phenotypes Prostate cancer Prostate carcinoma Prostate-Specific Antigen - metabolism Prostatic Neoplasms - blood supply Prostatic Neoplasms - pathology Pyrazoles - chemistry Pyrazoles - metabolism Pyrimidines - chemistry Pyrimidines - metabolism Radiology Research Article Sectioning Stroma Tumors Xenograft Model Antitumor Assays Xenografts Xenotransplantation
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