Pathophysiological characterization of MERRF patient-specific induced neurons generated by direct reprogramming

Mitochondrial diseases are a group of rare heterogeneous genetic disorders caused by total or partial mitochondrial dysfunction. They can be caused by mutations in nuclear or mitochondrial DNA (mtDNA). MERRF (Myoclonic Epilepsy with Ragged-Red Fibers) syndrome is one of the most common mitochondrial...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2019-05, Vol.1866 (5), p.861-881
Hauptverfasser:	Villanueva-Paz, Marina, Povea-Cabello, Suleva, Villalón-García, Irene, Suárez-Rivero, Juan M., Álvarez-Córdoba, Mónica, de la Mata, Mario, Talaverón-Rey, Marta, Jackson, Sandra, Sánchez-Alcázar, José A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Direct reprogramming Induced neurons MERRF Mitochondria Mitochondrial diseases
Online-Zugang:	Volltext
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