A minimum set of stable blocks for rational design of polypeptide chains

The aim of this work was to find a minimal set of structurally stable pentapeptides, which allows forming a polypeptide chain of a required 3D structure. To search for factors that ensure structural stability of the pentapeptide, we generated peptide sequences with no more than three functional grou...

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Veröffentlicht in:	Biochimie 2019-05, Vol.160, p.88-92
Hauptverfasser:	Nekrasov, Alexei N., Alekseeva, Ludmila G., Pogosyan, Rudolf А., Dolgikh, Dmitry A., Kirpichnikov, M.P., de Brevern, Alexandre G., Anashkina, Anastasia A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Local protein conformations Molecular dynamics Peptides Protein dynamics Protein structures Stable conformations
Online-Zugang:	Volltext
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