Multi-Reference Spectral Library Yields Almost Complete Coverage of Heterogeneous LC-MS/MS Data Sets

Spectral libraries play a central role in the analysis of data-independent-acquisition (DIA) proteomics experiments. A main assumption in current spectral library tools is that a single characteristic intensity pattern (CIP) suffices to describe the fragmentation of a peptide in a particular charge...

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Veröffentlicht in:	Journal of proteome research 2019-04, Vol.18 (4), p.1553-1566
Hauptverfasser:	Ammar, Constantin, Berchtold, Evi, Csaba, Gergely, Schmidt, Andreas, Imhof, Axel, Zimmer, Ralf
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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