Prevalence and Cellular Distribution of Novel Immune Checkpoint Targets Across Longitudinal Specimens in Treatment-naïve Melanoma Patients: Implications for Clinical Trials

Immunotherapies targeting costimulating and coinhibitory checkpoint receptors beyond PD-1 and CTLA-4 have entered clinical trials. Little is known about the relative abundance, coexpression, and immune cells enriched for each specific drug target, limiting understanding of the biological basis of po...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical cancer research 2019-06, Vol.25 (11), p.3247-3258
Hauptverfasser: Edwards, Jarem, Tasker, Annie, Pires da Silva, Inês, Quek, Camelia, Batten, Marcel, Ferguson, Angela, Allen, Ruth, Allanson, Benjamin, Saw, Robyn P M, Thompson, John F, Menzies, Alexander M, Palendira, Umaimainthan, Wilmott, James S, Long, Georgina V, Scolyer, Richard A
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!