Advanced glycation end-product 2 and Porphyromonas gingivalis lipopolysaccharide increase sclerostin expression in mouse osteocyte-like cells

Sclerostin is a secreted glycoprotein that is mainly expressed in osteocytes, exerts negative effects on bone formation, and is present at elevated levels in diabetes mellitus (DM). Periodontitis is an infectious disease caused by periodontopathic bacteria, a complication of DM, and sometimes associ...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2019-05, Vol.122, p.22-30
Hauptverfasser:	Sakamoto, Eijiro, Kido, Jun-ichi, Takagi, Ryosuke, Inagaki, Yuji, Naruishi, Koji, Nagata, Toshihiko, Yumoto, Hiromichi
Format:	Artikel
Sprache:	eng
Schlagworte:	AGEs Diabetes mellitus Osteocyte P-LPS Periodontitis Sclerostin
Online-Zugang:	Volltext
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