Intracellular dynamics of actin affects Borna disease virus replication in the nucleus

•Inhibition of the nucleocytoplasmic transport of actin affects BoDV replication.•Nuclear accumulation of actin results in the structural aberration in intranuclear viral factories of BoDV.•Inhibition of nuclear export of actin promotes the accumulation of viral proteins in the cytoplasm. Borna dise...

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Veröffentlicht in:	Virus research 2019-04, Vol.263, p.179-183
Hauptverfasser:	Hirai, Yuya, Domae, Eisuke, Yoshikawa, Yoshihiro, Okamura, Hideyuki, Makino, Akiko, Tomonaga, Keizo
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - metabolism Active Transport, Cell Nucleus Animals Borna disease virus (BoDV) Borna disease virus - physiology Cell Line Cell Nucleus - virology Exportin 6 Host-Pathogen Interactions Humans Importin 9 Karyopherins - metabolism Transcription Virus Replication
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