HLA-G allelic distribution in Sardinian children with Autism spectrum disorders: A replication study

•Replication study confirms immunogenetic association of HLA-G with ASD.•HLA-G alleles are significantly skewed in Sardinian ASD children.•Skewed HLA-G alleles seen in ASD might play a pathogenic role. Recent results show that in mainland Italian children with Autism spectrum disorder (ASD), HLA-G c...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2019-07, Vol.79, p.314-318
Hauptverfasser:	Guerini, Franca R., Bolognesi, Elisabetta, Sotgiu, Stefano, Carta, Alessandra, Clerici, Claudia, Chiappedi, Matteo, Ghezzo, Alessandro, Zanette, Michela, Mensi, Maria M., Canevini, Maria P., Zanzottera, Milena, Agliardi, Cristina, Costa, Andrea S., Balottin, Umberto, Clerici, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Autism Spectrum Disorder - genetics Autism Spectrum Disorder - immunology Autistic spectrum disorder Child Cohort Studies Ethnic Groups - genetics Exons - genetics Female Gene Frequency - genetics Genes, MHC Class I - genetics Genetic polymorphism Genetic Predisposition to Disease Genotype Haplotypes HLA-G HLA-G Antigens - genetics HLA-G Antigens - immunology Humans Immune system In utero immunology Italy KIR Male NK cells Polymorphism, Genetic - genetics
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