Polymers with distinctive anticancer mechanism that kills MDR cancer cells and inhibits tumor metastasis

Although mortality continues to decline over the past two decades, cancer is still a pervasive healthcare problem worldwide due to the increase in the number of cases, multidrug resistance (MDR) and metastasis. As a consequence of multidrug resistance, cancer treatment must rely on a host of chemoth...

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Veröffentlicht in:	Biomaterials 2019-04, Vol.199, p.76-87
Hauptverfasser:	Zhong, Guansheng, Yang, Chuan, Liu, Shaoqiong, Zheng, Yiran, Lou, Weiyang, Teo, Jye Yng, Bao, Chang, Cheng, Wei, Tan, Jeremy P.K., Gao, Shujun, Park, Nathaniel, Venkataraman, Shrinivas, Huang, Yuan, Tan, Min Han, Wang, Xiaojia, Hedrick, James L., Fan, Weimin, Yang, Yi Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer Functional polymers Guanidinium-functionalized polycarbonate Multidrug resistance Tumor metastasis
Online-Zugang:	Volltext
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