Effect of mechanical strain-induced PGE2 production on bone nodule formation by rat calvarial progenitor cells

High-magnitude mechanical strain inhibits bone nodule formation by reducing expression of bone morphogenetic protein-2 (BMP-2), Runt-related transcription factor 2 (Runx2), and muscle segment homeobox 2 (Msx2). Mechanical strain also induces production of proinflammatory factor prostaglandin E2 (PGE...

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Veröffentlicht in:	Journal of Oral Science 2019, Vol.61(1), pp.25-29
Hauptverfasser:	Takahashi, Yasuyo, Mayahara, Kotoe, Fushiki, Rena, Matsuike, Rieko, Shimizu, Noriyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	bone-nodule Dentistry mechanical strain osteoblast PGE2 Runx2
Online-Zugang:	Volltext
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