Use of Expression Profiles of HBV-DNA Integrated Into Genomes of Hepatocellular Carcinoma Cells to Select T Cells for Immunotherapy

Hepatocellular carcinoma (HCC) is often associated with hepatitis B virus (HBV) infection. Cells of most HBV-related HCCs contain HBV-DNA fragments that do not encode entire HBV antigens. We investigated whether these integrated HBV-DNA fragments encode epitopes that are recognized by T cells and wh...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2019-05, Vol.156 (6), p.1862-1876.e9
Hauptverfasser:	Tan, Anthony Tanoto, Yang, Ninghan, Lee Krishnamoorthy, Thinesh, Oei, Vincent, Chua, Alicia, Zhao, Xinyuan, Tan, Hui Si, Chia, Adeline, Le Bert, Nina, Low, Diana, Tan, Hiang Keat, Kumar, Rajneesh, Irani, Farah Gillan, Ho, Zi Zong, Zhang, Qi, Guccione, Ernesto, Wai, Lu-En, Koh, Sarene, Hwang, William, Chow, Wan Cheng, Bertoletti, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive T-cell Transfer HCC TCR TCR T-cell
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!