Rapid Differentiation of Multi-Zone Ocular Cells from Human Induced Pluripotent Stem Cells and Generation of Corneal Epithelial and Endothelial Cells

Eye is a complex organ with a highly specialized tissue structure. The establishment of human pluripotent stem cells (hPSCs) has allowed the simulation of eye development in vitro. Most differentiation works of hPSC-derived ocular cells focus on a single, tissue-specific lineage, however, that faces...

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Veröffentlicht in:	Stem cells and development 2019-04, Vol.28 (7), p.454-463
Hauptverfasser:	Li, Zongyi, Duan, Haoyun, Li, Wenjing, Hu, Xiaoli, Jia, Yanni, Zhao, Can, Zhang, Songmei, Zhou, Qingjun, Shi, Weiyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Culture Techniques Cell Differentiation Endothelial Cells - cytology Endothelial Cells - metabolism Epithelial Cells - cytology Epithelial Cells - metabolism Epithelium, Corneal - cytology Epithelium, Corneal - metabolism Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Original Research Reports
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