CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell–Dependent Control of Senescence

Inflammation in the liver provokes fibrosis, but inflammation is also important for tumor surveillance. Inhibitors of chemokine pathways, such as CXCL16 and CXCR6 regulation of lymphocyte trafficking, are being tested as antifibrotic agents, but their effects on the development of hepatocellular car...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2019-05, Vol.156 (6), p.1877-1889.e4
Hauptverfasser:	Mossanen, Jana C., Kohlhepp, Marlene, Wehr, Alexander, Krenkel, Oliver, Liepelt, Anke, Roeth, Anjali A., Möckel, Diana, Heymann, Felix, Lammers, Twan, Gassler, Nikolaus, Hermann, Juliane, Jankowski, Joachim, Neumann, Ulf P., Luedde, Tom, Trautwein, Christian, Tacke, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemokine Liver Cancer NKT Cells Senescence
Online-Zugang:	Volltext
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