Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations

General anesthetics have been used to ablate consciousness during surgery for more than 150 yr. Despite significant advances in our understanding of their molecular-level pharmacologic effects, comparatively little is known about how anesthetics alter brain dynamics to cause unconsciousness. Consequ...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2019-06, Vol.130 (6), p.1049-1063
Hauptverfasser:	Voss, Logan J, García, Paul S, Hentschke, Harald, Banks, Matthew I
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, General - administration & dosage Animals Cerebral Cortex - drug effects Cerebral Cortex - physiology Electroencephalography - drug effects Electroencephalography - methods Humans Nerve Net - drug effects Nerve Net - physiology Organ Culture Techniques
Online-Zugang:	Volltext
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