Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway

Coenzyme Q10 (CoQ10) is a well-known anti-adipogenic factor that possesses the capability to regulate non-alcoholic fatty liver disease (NAFLD). However, the mechanism by which CoQ10 acts on NAFLD is still unclear. In this study, the role of CoQ10 in the prevention of NAFLD was investigated in vivo...

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Veröffentlicht in:	Food & function 2019-02, Vol.10 (2), p.814-823
Hauptverfasser:	Chen, Ke, Chen, Xu, Xue, Hongliang, Zhang, Peiwen, Fang, Wanjun, Chen, Xuechen, Ling, Wenhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA carboxylase Carnitine Carnitine palmitoyltransferase Cholesterol Coenzyme Q10 Diet Fatty acids Fatty liver Fatty-acid synthase High fat diet Hyperlipidemia In vivo methods and tests Lipid metabolism Lipids Lipogenesis Liver Liver diseases Metabolism Mice Oxidation Palmitic acid Palmitoyltransferase Peroxisome proliferator-activated receptors Proteins Receptors Sodium Steatosis Sterol regulatory element-binding protein Triglycerides
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