IL-22-Independent Protection from Colitis in the Absence of Nkx2.3 Transcription Factor in Mice

The transcription factor Nkx2.3 regulates the vascular specification of Peyer patches in mice through determining endothelial addressin preference and may function as a susceptibility factor in inflammatory bowel diseases in humans. We wished to analyze the role of Nkx2.3 in colonic solitary intesti...

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Veröffentlicht in:	The Journal of immunology (1950) 2019-03, Vol.202 (6), p.1833-1844
Hauptverfasser:	Kellermayer, Zoltán, Vojkovics, Dóra, Dakah, Tareq Abu, Bodó, Kornélia, Botz, Bálint, Helyes, Zsuzsanna, Berta, Gergely, Kajtár, Béla, Schippers, Angela, Wagner, Norbert, Scotto, Luigi, O'Connor, Owen A, Arnold, Hans-Henning, Balogh, Péter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Colitis - immunology Colitis - metabolism Homeodomain Proteins - immunology Interleukin-22 Interleukins - metabolism Lymphocytes - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Peyer's Patches - immunology Peyer's Patches - metabolism Stromal Cells - immunology Transcription Factors - deficiency Transcription Factors - immunology
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