Hypoxia accelerates the progression of angiosarcoma through the regulation of angiosarcoma cells and tumor microenvironment

•Angiosarcoma is a rare malignant tumor derived from endothelial cells with a poor prognosis.•HIF-1α protein was over-expressed due to hypoxic conditions and there was heterogeneity of oxygen supply in angiosarcoma.•Hypoxia enhanced the proliferation, migration, and invasion abilities of angiosarcom...

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