Mannich Reactions of Carbohydrate Derivatives with Ketones To Afford Polyoxy-Functionalized Piperidines

Mannich reactions of carbohydrate derivatives with ketones that afford polyoxy-functionalized piperidines are reported. Ketone nucleophiles (enamines/enolates) were generated in the presence of the amines used for the formation of the iminium ions of sugar derivatives with or without an additive. Co...

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Veröffentlicht in:Organic letters 2019-02, Vol.21 (4), p.1165-1169
Hauptverfasser: Maram, Lingaiah, Tanaka, Fujie
Format: Artikel
Sprache:eng
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