Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia
The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients. to present results of analysis of the Instit...
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Veröffentlicht in: | Kardiologiia 2018-04, Vol.17 (4), p.22-35 |
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creator | Gromova, O A Torshin, I Y Kobalava, Z D Sorokina, M A Villevalde, S V Galochkin, S A Gogoleva, I V Gracheva, O N Grishina, T R Gromov, A N Egorova, E Y Kalacheva, A G Malyavskaya, S I Meraĭ, I A Semenov, V A |
description | The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients.
to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia.
The analysis was realized as analysis of data obtained in a cross-sectional study. In the cohort of patients (n=1453) formed from the IMBD adequacy of Mg supply was assessed by magnesium levels in blood plasma (Mg BP) (0.69±0.15 mmol/L) and estimates of daily Mg consumption according to dietary diaries (Mg D) (185±90 mg/day).
Mg supply was adequate (Mg BP >0.80 mmol/L, Mg D >300 mg/day) in not more than 6 % of patients. Presence of "Hypercoagulation" label in data base was associated with greater number of chronic diseases (2.3±2.1 and 0.83±0.8 with and without this label, respectively, р=0.0006) and elevated risk of the presence on 4 comorbid pathologies (odds ratio [OR] 18, 95 % confidence interval [CI] 10-25, р=0.0006). Mg deficit (Mg BP. |
doi_str_mv | 10.18087/cardio.2018.4.10106 |
format | Article |
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to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia.
The analysis was realized as analysis of data obtained in a cross-sectional study. In the cohort of patients (n=1453) formed from the IMBD adequacy of Mg supply was assessed by magnesium levels in blood plasma (Mg BP) (0.69±0.15 mmol/L) and estimates of daily Mg consumption according to dietary diaries (Mg D) (185±90 mg/day).
Mg supply was adequate (Mg BP >0.80 mmol/L, Mg D >300 mg/day) in not more than 6 % of patients. Presence of "Hypercoagulation" label in data base was associated with greater number of chronic diseases (2.3±2.1 and 0.83±0.8 with and without this label, respectively, р=0.0006) and elevated risk of the presence on 4 comorbid pathologies (odds ratio [OR] 18, 95 % confidence interval [CI] 10-25, р=0.0006). Mg deficit (Mg BP.</description><identifier>ISSN: 0022-9040</identifier><identifier>DOI: 10.18087/cardio.2018.4.10106</identifier><identifier>PMID: 29782257</identifier><language>eng ; rus</language><publisher>Russia (Federation)</publisher><subject>Adolescent ; Adult ; Cross-Sectional Studies ; Humans ; Magnesium ; Magnesium Deficiency ; Middle Aged ; Russia ; Young Adult</subject><ispartof>Kardiologiia, 2018-04, Vol.17 (4), p.22-35</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3016-3cd787a98e77db31476ea35f74d8e82e7a1cf33b97d5484bb3ea0c16dc0ca09d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29782257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gromova, O A</creatorcontrib><creatorcontrib>Torshin, I Y</creatorcontrib><creatorcontrib>Kobalava, Z D</creatorcontrib><creatorcontrib>Sorokina, M A</creatorcontrib><creatorcontrib>Villevalde, S V</creatorcontrib><creatorcontrib>Galochkin, S A</creatorcontrib><creatorcontrib>Gogoleva, I V</creatorcontrib><creatorcontrib>Gracheva, O N</creatorcontrib><creatorcontrib>Grishina, T R</creatorcontrib><creatorcontrib>Gromov, A N</creatorcontrib><creatorcontrib>Egorova, E Y</creatorcontrib><creatorcontrib>Kalacheva, A G</creatorcontrib><creatorcontrib>Malyavskaya, S I</creatorcontrib><creatorcontrib>Meraĭ, I A</creatorcontrib><creatorcontrib>Semenov, V A</creatorcontrib><creatorcontrib>State Budgetary Educational Institution "Samara State Medical University" of the RF Ministry of Health Care</creatorcontrib><creatorcontrib>Ivanovo State Medical Academy</creatorcontrib><creatorcontrib>Federal State Autonomous Educational Institution of Higher Education, "Peoples' Friendship University of Russia"</creatorcontrib><creatorcontrib>Northern State Medical University</creatorcontrib><creatorcontrib>Federal Research Center “Computer Science and Control” of Russian Academy of Science</creatorcontrib><creatorcontrib>Federal State Budget Educational Institution of Higher Education "Kemerovo State Medical Academy " the Ministry of Health of the Russian Federation</creatorcontrib><creatorcontrib>Federal State Budgetary Educational Institution of Higher Education, "M. V. Lomonosov Moscow State University"</creatorcontrib><title>Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia</title><title>Kardiologiia</title><addtitle>Kardiologiia</addtitle><description>The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients.
to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia.
The analysis was realized as analysis of data obtained in a cross-sectional study. In the cohort of patients (n=1453) formed from the IMBD adequacy of Mg supply was assessed by magnesium levels in blood plasma (Mg BP) (0.69±0.15 mmol/L) and estimates of daily Mg consumption according to dietary diaries (Mg D) (185±90 mg/day).
Mg supply was adequate (Mg BP >0.80 mmol/L, Mg D >300 mg/day) in not more than 6 % of patients. Presence of "Hypercoagulation" label in data base was associated with greater number of chronic diseases (2.3±2.1 and 0.83±0.8 with and without this label, respectively, р=0.0006) and elevated risk of the presence on 4 comorbid pathologies (odds ratio [OR] 18, 95 % confidence interval [CI] 10-25, р=0.0006). Mg deficit (Mg BP.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Cross-Sectional Studies</subject><subject>Humans</subject><subject>Magnesium</subject><subject>Magnesium Deficiency</subject><subject>Middle Aged</subject><subject>Russia</subject><subject>Young Adult</subject><issn>0022-9040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1r3DAQhnVoaUKaf1CKjr14O7JkS-5tSbpNICGhac9mLI0XgT-2khzYX9a_V-1ummtOAs3zvsPwMPZJwEoYMPqrxeD8vCpBmJVaCRBQv2PnAGVZNKDgjF3G6DuAutJSVdUHdlY22pRlpc_Z32vqvfWJzz2_x-1E0S8jx8nxp4SJ4uH_Zr-jYGfcLgMmP0_f-O2UaBjIpgUHvp5w2Ed_RK8xIX_oEvqJHN-EOXfxJxx3Ax3GjzlPU4p8vc1jYYoK-J4wxBN6T87b3HhY_xjoOaP-mfgGrR98TkbuJ_5zydfgR_a-xyHS5ct7wX5vvv-6uinuHn7cXq3vCitB1IW0ThuNjSGtXSeF0jWhrHqtnCFTkkZheym7RrtKGdV1khCsqJ0Fi9A4ecG-nHp3Yf6zUEzt6KPNx-NE8xLbUuhGqVpoeBsFVeoKatFkVJ1QG-YYA_XtLvgRw74V0B6ltiep7UFqq9qj1Bz7_LJh6UZyr6H_OuU_qBKiOA</recordid><startdate>201804</startdate><enddate>201804</enddate><creator>Gromova, O A</creator><creator>Torshin, I Y</creator><creator>Kobalava, Z D</creator><creator>Sorokina, M A</creator><creator>Villevalde, S V</creator><creator>Galochkin, S A</creator><creator>Gogoleva, I V</creator><creator>Gracheva, O N</creator><creator>Grishina, T R</creator><creator>Gromov, A N</creator><creator>Egorova, E Y</creator><creator>Kalacheva, A G</creator><creator>Malyavskaya, S I</creator><creator>Meraĭ, I A</creator><creator>Semenov, V A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201804</creationdate><title>Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia</title><author>Gromova, O A ; Torshin, I Y ; Kobalava, Z D ; Sorokina, M A ; Villevalde, S V ; Galochkin, S A ; Gogoleva, I V ; Gracheva, O N ; Grishina, T R ; Gromov, A N ; Egorova, E Y ; Kalacheva, A G ; Malyavskaya, S I ; Meraĭ, I A ; Semenov, V A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3016-3cd787a98e77db31476ea35f74d8e82e7a1cf33b97d5484bb3ea0c16dc0ca09d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; rus</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Cross-Sectional Studies</topic><topic>Humans</topic><topic>Magnesium</topic><topic>Magnesium Deficiency</topic><topic>Middle Aged</topic><topic>Russia</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gromova, O A</creatorcontrib><creatorcontrib>Torshin, I Y</creatorcontrib><creatorcontrib>Kobalava, Z D</creatorcontrib><creatorcontrib>Sorokina, M A</creatorcontrib><creatorcontrib>Villevalde, S V</creatorcontrib><creatorcontrib>Galochkin, S A</creatorcontrib><creatorcontrib>Gogoleva, I V</creatorcontrib><creatorcontrib>Gracheva, O N</creatorcontrib><creatorcontrib>Grishina, T R</creatorcontrib><creatorcontrib>Gromov, A N</creatorcontrib><creatorcontrib>Egorova, E Y</creatorcontrib><creatorcontrib>Kalacheva, A G</creatorcontrib><creatorcontrib>Malyavskaya, S I</creatorcontrib><creatorcontrib>Meraĭ, I A</creatorcontrib><creatorcontrib>Semenov, V A</creatorcontrib><creatorcontrib>State Budgetary Educational Institution "Samara State Medical University" of the RF Ministry of Health Care</creatorcontrib><creatorcontrib>Ivanovo State Medical Academy</creatorcontrib><creatorcontrib>Federal State Autonomous Educational Institution of Higher Education, "Peoples' Friendship University of Russia"</creatorcontrib><creatorcontrib>Northern State Medical University</creatorcontrib><creatorcontrib>Federal Research Center “Computer Science and Control” of Russian Academy of Science</creatorcontrib><creatorcontrib>Federal State Budget Educational Institution of Higher Education "Kemerovo State Medical Academy " the Ministry of Health of the Russian Federation</creatorcontrib><creatorcontrib>Federal State Budgetary Educational Institution of Higher Education, "M. 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V. Lomonosov Moscow State University"</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia</atitle><jtitle>Kardiologiia</jtitle><addtitle>Kardiologiia</addtitle><date>2018-04</date><risdate>2018</risdate><volume>17</volume><issue>4</issue><spage>22</spage><epage>35</epage><pages>22-35</pages><issn>0022-9040</issn><abstract>The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients.
to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia.
The analysis was realized as analysis of data obtained in a cross-sectional study. In the cohort of patients (n=1453) formed from the IMBD adequacy of Mg supply was assessed by magnesium levels in blood plasma (Mg BP) (0.69±0.15 mmol/L) and estimates of daily Mg consumption according to dietary diaries (Mg D) (185±90 mg/day).
Mg supply was adequate (Mg BP >0.80 mmol/L, Mg D >300 mg/day) in not more than 6 % of patients. Presence of "Hypercoagulation" label in data base was associated with greater number of chronic diseases (2.3±2.1 and 0.83±0.8 with and without this label, respectively, р=0.0006) and elevated risk of the presence on 4 comorbid pathologies (odds ratio [OR] 18, 95 % confidence interval [CI] 10-25, р=0.0006). Mg deficit (Mg BP.</abstract><cop>Russia (Federation)</cop><pmid>29782257</pmid><doi>10.18087/cardio.2018.4.10106</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Adolescent Adult Cross-Sectional Studies Humans Magnesium Magnesium Deficiency Middle Aged Russia Young Adult |
title | Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia |
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