Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia

The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients. to present results of analysis of the Instit...

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Veröffentlicht in:Kardiologiia 2018-04, Vol.17 (4), p.22-35
Hauptverfasser: Gromova, O A, Torshin, I Y, Kobalava, Z D, Sorokina, M A, Villevalde, S V, Galochkin, S A, Gogoleva, I V, Gracheva, O N, Grishina, T R, Gromov, A N, Egorova, E Y, Kalacheva, A G, Malyavskaya, S I, Meraĭ, I A, Semenov, V A
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container_issue 4
container_start_page 22
container_title Kardiologiia
container_volume 17
creator Gromova, O A
Torshin, I Y
Kobalava, Z D
Sorokina, M A
Villevalde, S V
Galochkin, S A
Gogoleva, I V
Gracheva, O N
Grishina, T R
Gromov, A N
Egorova, E Y
Kalacheva, A G
Malyavskaya, S I
Meraĭ, I A
Semenov, V A
description The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients. to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia. The analysis was realized as analysis of data obtained in a cross-sectional study. In the cohort of patients (n=1453) formed from the IMBD adequacy of Mg supply was assessed by magnesium levels in blood plasma (Mg BP) (0.69±0.15 mmol/L) and estimates of daily Mg consumption according to dietary diaries (Mg D) (185±90 mg/day). Mg supply was adequate (Mg BP >0.80 mmol/L, Mg D >300 mg/day) in not more than 6 % of patients. Presence of "Hypercoagulation" label in data base was associated with greater number of chronic diseases (2.3±2.1 and 0.83±0.8 with and without this label, respectively, р=0.0006) and elevated risk of the presence on 4 comorbid pathologies (odds ratio [OR] 18, 95 % confidence interval [CI] 10-25, р=0.0006). Mg deficit (Mg BP.
doi_str_mv 10.18087/cardio.2018.4.10106
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subjects Adolescent
Adult
Cross-Sectional Studies
Humans
Magnesium
Magnesium Deficiency
Middle Aged
Russia
Young Adult
title Deficit of Magnesium and States of Hypercoagulation: Intellectual Analysis of Data Obtained From a Sample of Patients Aged 18-50 years From Medical and Preventive Facilities in Russia
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