Brain iron accumulation in a blood donor family with restless legs syndrome

The pathophysiology of restless legs syndrome (RLS) is complex. Secondary RLS with iron deficiency -which suggests disturbed iron homeostasis- remains to be elucidated. We report the findings from a unique blood donor family with RLS. Three blood donors family members were diagnosed with RLS defined...

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Veröffentlicht in:	Revista de neurologiá 2019-02, Vol.68 (3), p.107-110
Hauptverfasser:	Lillo-Triguero, L, Del Castillo, A, Guzman de Villoria, J, Moran-Jimenez, M J, Guillem, A, Peraita-Adrados, R
Format:	Artikel
Sprache:	eng ; spa
Schlagworte:	Adult Aged Anemia, Iron-Deficiency - complications Basal Ganglia - chemistry Blood Donors Brain - diagnostic imaging Brain - metabolism Brain Chemistry Cerebellar Nuclei - chemistry Erythropoiesis Female Ferritins - blood Hemoglobins - analysis Humans Iron - analysis Iron - metabolism Iron - pharmacokinetics Magnetic Resonance Imaging Male Middle Aged Neuroimaging Pedigree Polysomnography Red Nucleus - chemistry Restless Legs Syndrome - genetics Restless Legs Syndrome - metabolism Smoking Substantia Nigra - chemistry Transferrin - analysis Vitamin B 12 Deficiency - complications
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