Irregular pacing of ventricular cardiomyocytes induces pro‐fibrotic signalling involving paracrine effects of transforming growth factor beta and connective tissue growth factor

Aims Atrial fibrillation is the most prevalent sustained arrhythmia associated with arrhythmic ventricular contractions, incident heart failure, increased morbidity and mortality. The relationship between arrhythmic contractions and ventricular remodelling is incompletely understood. The aim of this...

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Veröffentlicht in:	European journal of heart failure 2019-04, Vol.21 (4), p.482-491
Hauptverfasser:	Slawik, Jonathan, Adrian, Lucas, Hohl, Mathias, Lothschütz, Sarah, Laufs, Ulrich, Böhm, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrhythmia Atrial fibrillation Fibrosis Oxidative stress
Online-Zugang:	Volltext
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