Newly identified set of obesity‐related genotypes and abdominal fat influence the risk of insulin resistance in a Korean population

We aimed to identify obesity‐related single‐nucleotide polymorphism (SNP) loci in a Korean population and construct an obesity genetic risk score (GRS) to examine the association of the genetic predisposition to obesity with insulin resistance (IR). In total, 9675 subjects were included, and 7666 of...

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Veröffentlicht in:	Clinical genetics 2019-04, Vol.95 (4), p.488-495
Hauptverfasser:	Kim, Minjoo, Jeong, Sarang, Yoo, Hye Jin, An, Hyoeun, Jee, Sun Ha, Lee, Jong Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Abdominal Fat abdominal obesity Adiponectin Alanine Alanine transaminase Alleles Biomarkers Blood pressure Body mass index Female Gene polymorphism Genetic Predisposition to Disease genetic risk score genome‐wide association study Genotype Health risk assessment Humans Insulin Insulin resistance Insulin Resistance - genetics Male Obesity Obesity - epidemiology Obesity - etiology Obesity - metabolism Odds Ratio Polymorphism, Single Nucleotide Public Health Surveillance Quantitative Trait Loci Quantitative Trait, Heritable Republic of Korea - epidemiology Retrospective Studies Single-nucleotide polymorphism
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