Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2)

To evaluate netarsudil 0.02% ophthalmic solution in patients with open-angle glaucoma (OAG) and ocular hypertension (OHT). Double-masked, randomized, multicenter, parallel-group, noninferiority clinical study. After a washout of all prestudy ocular hypotensive medications, 756 eligible patients with...

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Veröffentlicht in:	American journal of ophthalmology 2019-04, Vol.200, p.130-137
Hauptverfasser:	Kahook, Malik Y., Serle, Janet B., Mah, Francis S., Kim, Terry, Raizman, Michael B., Heah, Theresa, Ramirez-Davis, Nancy, Kopczynski, Casey C., Usner, Dale W., Novack, Gary D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Ophthalmic Adrenergic beta-Antagonists - administration & dosage Adrenergic beta-Antagonists - therapeutic use Adult Aged Antihypertensive Agents - administration & dosage Antihypertensive Agents - adverse effects Antihypertensive Agents - therapeutic use Benzoates - administration & dosage Benzoates - adverse effects Benzoates - therapeutic use beta-Alanine - administration & dosage beta-Alanine - adverse effects beta-Alanine - analogs & derivatives beta-Alanine - therapeutic use Consent Cornea Diabetic retinopathy Double-Blind Method Edema FDA approval Female Glaucoma Glaucoma, Open-Angle - diagnosis Glaucoma, Open-Angle - drug therapy Glaucoma, Open-Angle - physiopathology Humans Intraocular Pressure - drug effects Male Middle Aged Ocular Hypertension - diagnosis Ocular Hypertension - drug therapy Ocular Hypertension - physiopathology Ophthalmic Solutions Ophthalmology rho-Associated Kinases - antagonists & inhibitors Timolol - administration & dosage Timolol - therapeutic use Treatment Outcome
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