Exploring electrostatic interactions of relaxin family peptide receptor 3 and 4 with ligands using a NanoBiT-based binding assay

Relaxin family peptides perform a variety of biological functions by activating four G protein-coupled receptors, namely relaxin family peptide receptor 1-4 (RXFP1-4). We recently disclosed electrostatic interactions of the homologous RXFP3 and RXFP4 with some agonists based on activation complement...

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Veröffentlicht in:Biochimica et biophysica acta. Biomembranes 2019-04, Vol.1861 (4), p.776-786
Hauptverfasser: Wang, Jia-Hui, Nie, Wei-Han, Shao, Xiao-Xia, Li, Hao-Zheng, Hu, Meng-Jun, Liu, Ya-Li, Xu, Zeng-Guang, Guo, Zhan-Yun
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Sprache:eng
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