Real-world studies no substitute for RCTs in establishing efficacy

[...]rapid increases in the availability of registries, electronic health records, and insurance claims, and the ability to access, process, link, and analyse data from these sources at fairly low cost lend support for calls to replace randomised controlled trials (RCTs) with so-called real-world st...

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Veröffentlicht in:	The Lancet (British edition) 2019-01, Vol.393 (10168), p.210-211
Hauptverfasser:	Gerstein, Hertzel C, McMurray, John, Holman, Rury R
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical trials Cost analysis Data processing Diabetes Diabetes mellitus Drug Approval - methods Effectiveness Electronic health records Electronic medical records Humans Insulin Mortality Observational studies Observational Studies as Topic Pragmatic Clinical Trials as Topic Randomization Randomized Controlled Trials as Topic - economics Randomized Controlled Trials as Topic - standards Research Design - standards Therapy
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