Magnesium lithospermate B prevents phenotypic transformation of pulmonary arteries in rats with hypoxic pulmonary hypertension through suppression of NADPH oxidase

Magnesium lithospermate B (MLB) shows multiple biological activities including anti-oxidation and anti-proliferation in various diseases. However, the function of MLB in pulmonary arterial hypertension (PAH) is still unknown. This study aims to investigate the effect of MLB on hypoxia-induced phenot...

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Veröffentlicht in:	European journal of pharmacology 2019-03, Vol.847, p.32-41
Hauptverfasser:	Li, Tao, Luo, Xiu-Ju, Wang, E-Li, Li, Nian-Sheng, Zhang, Xiao-Jie, Song, Feng-Lin, Yang, Jin-Fu, Liu, Bin, Peng, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Magnesium lithospermate B NADPH oxidase Phenotypic transformation Pulmonary arterial hypertension Pulmonary vascular remodeling
Online-Zugang:	Volltext
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