Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study
To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls. Retrospective cohort study. Public county hospital. 821 patients undergoing general anesthesia. Incidence of hemodynamic events, defined by a mean arter...
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Veröffentlicht in: | Journal of clinical anesthesia 2019-08, Vol.55, p.146-150 |
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container_title | Journal of clinical anesthesia |
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creator | Moon, Tiffany S. Gonzales, Michael X. Sun, Joshua J. Kim, Agnes Fox, Pamela E. Minhajuddin, Abu T. Pak, Taylor J. Ogunnaike, Babatunde |
description | To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls.
Retrospective cohort study.
Public county hospital.
821 patients undergoing general anesthesia.
Incidence of hemodynamic events, defined by a mean arterial pressure of 105 mmHg or a heart rate of 100 beats per minute.
Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
•Cocaine-positive patients did not have more hemodynamic events.•Length of stay and in-hospital mortality did not differ in the two groups.•Cocaine-positive patients did not require more vasopressors intraoperatively. |
doi_str_mv | 10.1016/j.jclinane.2018.12.028 |
format | Article |
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Retrospective cohort study.
Public county hospital.
821 patients undergoing general anesthesia.
Incidence of hemodynamic events, defined by a mean arterial pressure of <65 mmHg or >105 mmHg or a heart rate of <50 beats per minute or >100 beats per minute.
Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
•Cocaine-positive patients did not have more hemodynamic events.•Length of stay and in-hospital mortality did not differ in the two groups.•Cocaine-positive patients did not require more vasopressors intraoperatively.</description><identifier>ISSN: 0952-8180</identifier><identifier>EISSN: 1873-4529</identifier><identifier>DOI: 10.1016/j.jclinane.2018.12.028</identifier><identifier>PMID: 30660093</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anesthesia ; Blood & organ donations ; Blood pressure ; Cardiac arrhythmia ; Cocaine ; Cocaine-related disorders ; Cohort analysis ; Drug administration ; Drug dosages ; Family medical history ; Heart rate ; Hemodynamics ; Hospitals ; Hypertension ; Intraoperative care ; Medical records ; Metabolites ; Mortality ; Patients ; Sinuses ; Standard deviation ; Statistical analysis ; Surgery ; Toxicology ; Urine ; Vasopressors</subject><ispartof>Journal of clinical anesthesia, 2019-08, Vol.55, p.146-150</ispartof><rights>2018</rights><rights>Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Aug 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-a6caaae704e2c9d51f87459913d8d91958bc2303e76b5683d4aefab0e8404b483</citedby><cites>FETCH-LOGICAL-c396t-a6caaae704e2c9d51f87459913d8d91958bc2303e76b5683d4aefab0e8404b483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2191338107?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976,64364,64366,64368,72218</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30660093$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moon, Tiffany S.</creatorcontrib><creatorcontrib>Gonzales, Michael X.</creatorcontrib><creatorcontrib>Sun, Joshua J.</creatorcontrib><creatorcontrib>Kim, Agnes</creatorcontrib><creatorcontrib>Fox, Pamela E.</creatorcontrib><creatorcontrib>Minhajuddin, Abu T.</creatorcontrib><creatorcontrib>Pak, Taylor J.</creatorcontrib><creatorcontrib>Ogunnaike, Babatunde</creatorcontrib><title>Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study</title><title>Journal of clinical anesthesia</title><addtitle>J Clin Anesth</addtitle><description>To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls.
Retrospective cohort study.
Public county hospital.
821 patients undergoing general anesthesia.
Incidence of hemodynamic events, defined by a mean arterial pressure of <65 mmHg or >105 mmHg or a heart rate of <50 beats per minute or >100 beats per minute.
Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
•Cocaine-positive patients did not have more hemodynamic events.•Length of stay and in-hospital mortality did not differ in the two groups.•Cocaine-positive patients did not require more vasopressors intraoperatively.</description><subject>Anesthesia</subject><subject>Blood & organ donations</subject><subject>Blood pressure</subject><subject>Cardiac arrhythmia</subject><subject>Cocaine</subject><subject>Cocaine-related disorders</subject><subject>Cohort analysis</subject><subject>Drug administration</subject><subject>Drug dosages</subject><subject>Family medical history</subject><subject>Heart rate</subject><subject>Hemodynamics</subject><subject>Hospitals</subject><subject>Hypertension</subject><subject>Intraoperative care</subject><subject>Medical records</subject><subject>Metabolites</subject><subject>Mortality</subject><subject>Patients</subject><subject>Sinuses</subject><subject>Standard deviation</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Toxicology</subject><subject>Urine</subject><subject>Vasopressors</subject><issn>0952-8180</issn><issn>1873-4529</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU9v1DAQxS0EokvhK1SWuHBJGNuJY3OiqvgnVUJCcLYce9J1lDiLnay03x6vtuXAhZMP_r03M-8RcsOgZsDk-7Ee3RSijVhzYKpmvAaunpEdU52ompbr52QHuuWVYgquyKucRwAoH-wluRIgJYAWO5J-oMO4Urc4GyLSLSO10dN1jzREFzxGh3QZ6B7nxZ-inYOjeCySTP2WQnygDxgx2anIMBdZDvYDvaUJ17TkA7o1HLHY75e00rxu_vSavBjslPHN43tNfn3-9PPua3X__cu3u9v7ygkt18pKZ63FDhrkTvuWDaprWq2Z8MprplvVOy5AYCf7VirhG4uD7QFVA03fKHFN3l18D2n5vZXdzByyw2kqiy5bNpx1WijZSl7Qt_-g47KlWLYrVJkoFIOuUPJCuXJZTjiYQwqzTSfDwJxbMaN5asWcWzGMm9JKEd482m_9jP6v7KmGAny8AFjyOAZMJrtwTt6HVBI0fgn_m_EHUd-iPg</recordid><startdate>20190801</startdate><enddate>20190801</enddate><creator>Moon, Tiffany S.</creator><creator>Gonzales, Michael X.</creator><creator>Sun, Joshua J.</creator><creator>Kim, Agnes</creator><creator>Fox, Pamela E.</creator><creator>Minhajuddin, Abu T.</creator><creator>Pak, Taylor J.</creator><creator>Ogunnaike, Babatunde</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20190801</creationdate><title>Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study</title><author>Moon, Tiffany S. ; Gonzales, Michael X. ; Sun, Joshua J. ; Kim, Agnes ; Fox, Pamela E. ; Minhajuddin, Abu T. ; Pak, Taylor J. ; Ogunnaike, Babatunde</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-a6caaae704e2c9d51f87459913d8d91958bc2303e76b5683d4aefab0e8404b483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Anesthesia</topic><topic>Blood & organ donations</topic><topic>Blood pressure</topic><topic>Cardiac arrhythmia</topic><topic>Cocaine</topic><topic>Cocaine-related disorders</topic><topic>Cohort analysis</topic><topic>Drug administration</topic><topic>Drug dosages</topic><topic>Family medical history</topic><topic>Heart rate</topic><topic>Hemodynamics</topic><topic>Hospitals</topic><topic>Hypertension</topic><topic>Intraoperative care</topic><topic>Medical records</topic><topic>Metabolites</topic><topic>Mortality</topic><topic>Patients</topic><topic>Sinuses</topic><topic>Standard deviation</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Toxicology</topic><topic>Urine</topic><topic>Vasopressors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moon, Tiffany S.</creatorcontrib><creatorcontrib>Gonzales, Michael X.</creatorcontrib><creatorcontrib>Sun, Joshua J.</creatorcontrib><creatorcontrib>Kim, Agnes</creatorcontrib><creatorcontrib>Fox, Pamela E.</creatorcontrib><creatorcontrib>Minhajuddin, Abu T.</creatorcontrib><creatorcontrib>Pak, Taylor J.</creatorcontrib><creatorcontrib>Ogunnaike, Babatunde</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moon, Tiffany S.</au><au>Gonzales, Michael X.</au><au>Sun, Joshua J.</au><au>Kim, Agnes</au><au>Fox, Pamela E.</au><au>Minhajuddin, Abu T.</au><au>Pak, Taylor J.</au><au>Ogunnaike, Babatunde</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study</atitle><jtitle>Journal of clinical anesthesia</jtitle><addtitle>J Clin Anesth</addtitle><date>2019-08-01</date><risdate>2019</risdate><volume>55</volume><spage>146</spage><epage>150</epage><pages>146-150</pages><issn>0952-8180</issn><eissn>1873-4529</eissn><abstract>To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls.
Retrospective cohort study.
Public county hospital.
821 patients undergoing general anesthesia.
Incidence of hemodynamic events, defined by a mean arterial pressure of <65 mmHg or >105 mmHg or a heart rate of <50 beats per minute or >100 beats per minute.
Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
•Cocaine-positive patients did not have more hemodynamic events.•Length of stay and in-hospital mortality did not differ in the two groups.•Cocaine-positive patients did not require more vasopressors intraoperatively.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30660093</pmid><doi>10.1016/j.jclinane.2018.12.028</doi><tpages>5</tpages></addata></record> |
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subjects | Anesthesia Blood & organ donations Blood pressure Cardiac arrhythmia Cocaine Cocaine-related disorders Cohort analysis Drug administration Drug dosages Family medical history Heart rate Hemodynamics Hospitals Hypertension Intraoperative care Medical records Metabolites Mortality Patients Sinuses Standard deviation Statistical analysis Surgery Toxicology Urine Vasopressors |
title | Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study |
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