Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study

To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls. Retrospective cohort study. Public county hospital. 821 patients undergoing general anesthesia. Incidence of hemodynamic events, defined by a mean arter...

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Veröffentlicht in:Journal of clinical anesthesia 2019-08, Vol.55, p.146-150
Hauptverfasser: Moon, Tiffany S., Gonzales, Michael X., Sun, Joshua J., Kim, Agnes, Fox, Pamela E., Minhajuddin, Abu T., Pak, Taylor J., Ogunnaike, Babatunde
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container_end_page 150
container_issue
container_start_page 146
container_title Journal of clinical anesthesia
container_volume 55
creator Moon, Tiffany S.
Gonzales, Michael X.
Sun, Joshua J.
Kim, Agnes
Fox, Pamela E.
Minhajuddin, Abu T.
Pak, Taylor J.
Ogunnaike, Babatunde
description To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls. Retrospective cohort study. Public county hospital. 821 patients undergoing general anesthesia. Incidence of hemodynamic events, defined by a mean arterial pressure of 105 mmHg or a heart rate of 100 beats per minute. Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts. Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls. •Cocaine-positive patients did not have more hemodynamic events.•Length of stay and in-hospital mortality did not differ in the two groups.•Cocaine-positive patients did not require more vasopressors intraoperatively.
doi_str_mv 10.1016/j.jclinane.2018.12.028
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source Elsevier ScienceDirect Journals; ProQuest Central UK/Ireland
subjects Anesthesia
Blood & organ donations
Blood pressure
Cardiac arrhythmia
Cocaine
Cocaine-related disorders
Cohort analysis
Drug administration
Drug dosages
Family medical history
Heart rate
Hemodynamics
Hospitals
Hypertension
Intraoperative care
Medical records
Metabolites
Mortality
Patients
Sinuses
Standard deviation
Statistical analysis
Surgery
Toxicology
Urine
Vasopressors
title Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study
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