Effects of cannabis tetrahydrocannabinol on endocannabinoid homeostasis in human placenta

Cannabis use has become a hot topic in several countries due to the debate about its legalization for medical purposes. However, data are limited regarding adverse events, safety and potential impact on reproductive health. Cannabis consumption during pregnancy has been associated with gestational d...

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Veröffentlicht in:	Archives of toxicology 2019-03, Vol.93 (3), p.649-658
Hauptverfasser:	Maia, J., Midão, L., Cunha, S. C., Almada, M., Fonseca, B. M., Braga, J., Gonçalves, D., Teixeira, N., Correia-da-Silva, Georgina
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidohydrolases - metabolism Anandamide Arachidonic Acids - metabolism Biomedical and Life Sciences Biomedicine Birth weight Cannabinoid CB1 receptors Cannabinoid CB2 receptors Cannabis Dronabinol - toxicity Drug abuse Endocannabinoid system Endocannabinoids - metabolism Environmental Health Fatty acids Fatty-acid amide hydrolase Female Health care Homeostasis Homeostasis - drug effects Humans Hydrolase Low birth weight Marijuana Miscarriage Molecular Toxicology Occupational Medicine/Industrial Medicine Pharmacology/Toxicology Phospholipase Phospholipase D Placenta Placenta - drug effects Placenta - physiology Polyunsaturated Alkamides - metabolism Pregnancy Premature birth Psychotropic Drugs - toxicity Receptor, Cannabinoid, CB1 - metabolism Receptors Reproductive health Tetrahydrocannabinol Weight
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