Ischemia/Reperfusion Injury in the Aged Liver: The Importance of the Sinusoidal Endothelium in Developing Therapeutic Strategies for the Elderly

Abstract The liver endothelium plays a key role in the progression and resolution of liver diseases in young and adult individuals. However, its role in older people remains unknown. We have herein evaluated the importance of the sinusoidal endothelium in the pathophysiology of acute liver injury, a...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2020-02, Vol.75 (2), p.268-277
Hauptverfasser:	Hide, Diana, Warren, Alessandra, Fernández-Iglesias, Anabel, Maeso-Díaz, Raquel, Peralta, Carmen, Le Couteur, David G, Bosch, Jaime, Cogger, Victoria C, Gracia-Sancho, Jordi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Drug therapy Endothelium Geriatrics Hepatocytes Ischemia Liver diseases Older people Pathophysiology Phenotypes Reperfusion Simvastatin Vasodilation
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