Surgical aortic valve replacement and patient-prosthesis mismatch: a meta-analysis of 108 182 patients

This study sought to evaluate the impact of patient-prosthesis mismatch (PPM) on the risk of perioperative, early-, mid- and long-term mortality rates after surgical aortic valve replacement. Databases were searched for studies published until March 2018. The main outcomes of interest were periopera...

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Veröffentlicht in:European journal of cardio-thoracic surgery 2019-07, Vol.56 (1), p.44-54
Hauptverfasser: Sá, Michel Pompeu Barros de Oliveira, de Carvalho, Martinha Millianny Barros, Sobral Filho, Dário Celestino, Cavalcanti, Luiz Rafael Pereira, Rayol, Sérgio da Costa, Diniz, Roberto Gouvea Silva, Menezes, Alexandre Motta, Clavel, Marie-Annick, Pibarot, Philippe, Lima, Ricardo Carvalho
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container_title European journal of cardio-thoracic surgery
container_volume 56
creator Sá, Michel Pompeu Barros de Oliveira
de Carvalho, Martinha Millianny Barros
Sobral Filho, Dário Celestino
Cavalcanti, Luiz Rafael Pereira
Rayol, Sérgio da Costa
Diniz, Roberto Gouvea Silva
Menezes, Alexandre Motta
Clavel, Marie-Annick
Pibarot, Philippe
Lima, Ricardo Carvalho
description This study sought to evaluate the impact of patient-prosthesis mismatch (PPM) on the risk of perioperative, early-, mid- and long-term mortality rates after surgical aortic valve replacement. Databases were searched for studies published until March 2018. The main outcomes of interest were perioperative mortality, 1-year mortality, 5-year mortality and 10-year mortality. The search yielded 3761 studies for inclusion. Of these, 70 articles were analysed, and their data were extracted. The total number of patients included was 108 182 who underwent surgical aortic valve replacement. The incidence of PPM after surgical aortic valve replacement was 53.7% (58 116 with PPM and 50 066 without PPM). Perioperative mortality [odds ratio (OR) 1.491, 95% confidence interval (CI) 1.302-1.707; P 
doi_str_mv 10.1093/ejcts/ezy466
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Databases were searched for studies published until March 2018. The main outcomes of interest were perioperative mortality, 1-year mortality, 5-year mortality and 10-year mortality. The search yielded 3761 studies for inclusion. Of these, 70 articles were analysed, and their data were extracted. The total number of patients included was 108 182 who underwent surgical aortic valve replacement. The incidence of PPM after surgical aortic valve replacement was 53.7% (58 116 with PPM and 50 066 without PPM). Perioperative mortality [odds ratio (OR) 1.491, 95% confidence interval (CI) 1.302-1.707; P &lt; 0.001], 1-year mortality (OR 1.465, 95% CI 1.277-1.681; P &lt; 0.001), 5-year mortality (OR 1.358, 95% CI 1.218-1.515; P &lt; 0.001) and 10-year mortality (OR 1.534, 95% CI 1.290-1.825; P &lt; 0.001) were increased in patients with PPM. 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title Surgical aortic valve replacement and patient-prosthesis mismatch: a meta-analysis of 108 182 patients
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