GABAAR Modulator for Postpartum Depression
During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synth...
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Veröffentlicht in: | Cell 2019-01, Vol.176 (1-2), p.1-1 |
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description | During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.
During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF. |
doi_str_mv | 10.1016/j.cell.2018.12.016 |
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During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.</description><identifier>ISSN: 0092-8674</identifier><identifier>EISSN: 1097-4172</identifier><identifier>DOI: 10.1016/j.cell.2018.12.016</identifier><language>eng</language><publisher>Elsevier Inc</publisher><ispartof>Cell, 2019-01, Vol.176 (1-2), p.1-1</ispartof><rights>2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2926-a90a9d7f6b8a40d452939852587cf39817d3da4e74a59150e1f8f56df21209723</citedby><cites>FETCH-LOGICAL-c2926-a90a9d7f6b8a40d452939852587cf39817d3da4e74a59150e1f8f56df21209723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.cell.2018.12.016$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids></links><search><creatorcontrib>Mody, Istvan</creatorcontrib><title>GABAAR Modulator for Postpartum Depression</title><title>Cell</title><description>During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.
During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.</description><issn>0092-8674</issn><issn>1097-4172</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMouK7-AU97FKE1kzZNAl7q1yqsKKLnEPMBWbqbmrSC_96UevYwzDC8zzDvi9A54BIwNFfbUtuuKwkGXgIp8-oALQALVtTAyCFaYCxIwRtWH6OTlLYYY04pXaDLdXvTtm-r52DGTg0hrlyu15CGXsVh3K3ubB9tSj7sT9GRU12yZ399iT4e7t9vH4vNy_rptt0UmgjSFEpgJQxzzSdXNTY1JaISnBLKmXZ5AmYqo2rLakUFUGzBcUcb4wiQ_DCpluhivtvH8DXaNMidT5M9tbdhTJIAExWDWUpmqY4hpWid7KPfqfgjAcspGLmVEymnYCQQmVcZup4hm018extl0t7utTU-Wj1IE_x_-C8K32lj</recordid><startdate>20190110</startdate><enddate>20190110</enddate><creator>Mody, Istvan</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20190110</creationdate><title>GABAAR Modulator for Postpartum Depression</title><author>Mody, Istvan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2926-a90a9d7f6b8a40d452939852587cf39817d3da4e74a59150e1f8f56df21209723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mody, Istvan</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mody, Istvan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>GABAAR Modulator for Postpartum Depression</atitle><jtitle>Cell</jtitle><date>2019-01-10</date><risdate>2019</risdate><volume>176</volume><issue>1-2</issue><spage>1</spage><epage>1</epage><pages>1-1</pages><issn>0092-8674</issn><eissn>1097-4172</eissn><abstract>During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.
During the postpartum period, the brain’s inhibitory GABAA receptors may not recover in time following their reduced numbers during pregnancy. This is likely the cause of postpartum depression prevalent in ∼12% of childbearing women. A new therapy for this condition consists of administering a synthetic neurosteroid during the postpartum period to alleviate the mood disorder. To view this Bench to Bedside, open or download the PDF.</abstract><pub>Elsevier Inc</pub><doi>10.1016/j.cell.2018.12.016</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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title | GABAAR Modulator for Postpartum Depression |
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