Cholesterol Flip-Flop in Heterogeneous Membranes

Cholesterol is the most abundant molecule in the plasma membrane of mammals. Its distribution across the two membrane leaflets is critical for understanding how cells work. Cholesterol trans-bilayer motion (flip-flop) is a key process influencing its distribution in membranes. Despite extensive inve...

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Veröffentlicht in:	Journal of chemical theory and computation 2019-03, Vol.15 (3), p.2064-2070
Hauptverfasser:	Gu, Ruo-Xu, Baoukina, Svetlana, Tieleman, D. Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholesterol Dependence Environmental impact Lipids Membranes Molecular dynamics
Online-Zugang:	Volltext
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