Role of Mediator in virulence and antifungal drug resistance in pathogenic fungi

Mediator complex has recently emerged as an important regulator of gene expression in pathogenic fungi. Mediator is a multi-subunit complex of polypeptides involved in transcriptional activation in eukaryotes, with roles including preinitiation complex (PIC) assembly and chromatin remodeling. Within...

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Veröffentlicht in:	Current genetics 2019-06, Vol.65 (3), p.621-630
Hauptverfasser:	Moran, Gary P., Anderson, Matthew Z., Myers, Lawrence C., Sullivan, Derek J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal agents Biochemistry Biomedical and Life Sciences Cell Biology Chromatin remodeling Drug development Drug resistance Eukaryotes Fungi Fungicides Gene expression Life Sciences Microbial Genetics and Genomics Microbiology Pathogens Plant Sciences Polypeptides Proteomics Review Transcription activation Virulence
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