The impact of high PD-L1 expression on the surrogate endpoints and clinical outcomes of anti-PD-1/PD-L1 antibodies in non-small cell lung cancer

•The hazard ratio of OS was strongly correlated with hazard ratio of PFS in all patients in ICI trials.•Especially in patients with high PD-L1 expression, ORR and PFS was correlated with OS.•These surrogate endpoints may be considered in accordance with the design of the trials to evaluate the effic...

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