Blood group alters platelet binding kinetics to von Willebrand factor and consequently platelet function

Blood type O is associated with a lower risk of myocardial infarction. Platelets play a critical role in myocardial infarction. It is not known whether the expression of blood group antigens on platelet proteins alters platelet function; we hypothesized that platelet function would be different betw...

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Veröffentlicht in:	Blood 2019-03, Vol.133 (12), p.1371-1377
Hauptverfasser:	Dunne, Eimear, Qi, Qin M., Shaqfeh, Eric S., O'Sullivan, Jamie M., Schoen, Ingmar, Ricco, Antonio J., O'Donnell, James S., Kenny, Dermot
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Group Antigens - physiology Blood Platelets - physiology Female Follow-Up Studies Humans Kinetics Male Platelet Adhesiveness Platelet Aggregation Platelet Glycoprotein GPIb-IX Complex - metabolism Protein Binding von Willebrand Factor - metabolism
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