Differential Hepatotoxic Effects of Sodium Valproate at Different Doses in Albino Rats

Background Liver plays an essential role for transforming and clearing chemicals that may cause harmful effects to it. Sodium Valproate, renowned to be a potent antiepileptic drug, when taken in overdose may cause toxic effects to liver and other organs as well. Liver damage can be assessed with his...

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Veröffentlicht in:	Kathmandu University medical journal 2018-01, Vol.16 (61), p.78-82
Hauptverfasser:	Shakya, R, Hoque, M K, Sapkota, A S, Gupta, P K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Animals Anticonvulsants - toxicity Aspartate Aminotransferases - blood Dose-Response Relationship, Drug Liver - drug effects Liver - enzymology Liver - injuries Male Rats Rats, Wistar Skin Diseases - chemically induced Valproic Acid - therapeutic use Valproic Acid - toxicity
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