EGFR (Epidermal Growth Factor Receptor) Signaling and the Mitochondria Regulate sFlt-1 (Soluble FMS-Like Tyrosine Kinase-1) Secretion

Preeclampsia is a hypertensive disorder of pregnancy characterized by maternal endothelial dysfunction and end-organ damage. The antiangiogenic factor, sFlt-1 (soluble FMS-like tyrosine kinase-1) has been strongly implicated in the pathogenesis of preeclampsia. sFlt-1 is secreted into the maternal c...

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Veröffentlicht in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2019-03, Vol.73 (3), p.659-670
Hauptverfasser: Hastie, Roxanne, Brownfoot, Fiona C, Pritchard, Natasha, Hannan, Natalie J, Cannon, Ping, Nguyen, Vi, Palmer, Kirsten, Beard, Sally, Tong, Stephen, Kaitu’u-Lino, Tu’uhevaha J
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Sprache:eng
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