Silence of lncRNA UCA1 rescues drug resistance of cisplatin to non–small‐cell lung cancer cells

The aim of this study was to investigate the effect of long noncoding RNA (lncRNA) urogenital carcinoma antigen 1 (UCA1) on drug resistance in A549/DDP cell and explore its underlying mechanism. The inhibition rate and IC 50 of DDP were detected in A549 and A549/DDP cells by 3‐(4,5‐dimethylthiazol‐2...

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Veröffentlicht in:	Journal of cellular biochemistry 2019-06, Vol.120 (6), p.9243-9249
Hauptverfasser:	Liu, Xiaojing, Huang, Zhisheng, Qian, Wei, Zhang, Qing, Sun, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell adhesion & migration Cell migration Chemotherapy Cisplatin Drug resistance epithelial‐mesenchymal transition Genital cancers invasion Lung cancer Mesenchyme migration non–small‐cell lung cancer cells Polymerase chain reaction Ribonucleic acid RNA urogenital carcinoma antigen 1 Vimentin
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