Mitochondria-targeted antioxidant delivery for precise treatment of myocardial ischemia–reperfusion injury through a multistage continuous targeted strategy

Efficient delivery of antioxidant drugs into mitochondria of ischemic cardiomyocytes where reactive oxygen species largely induced is a major challenge for precise treatment of myocardial ischemia–reperfusion injury. Herein, we report a smart dual-shell polymeric nanoparticle, MCTD-NPs, which utiliz...

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Veröffentlicht in:	Nanomedicine 2019-02, Vol.16, p.236-249
Hauptverfasser:	Cheng, Ying, Liu, Dao-zhou, Zhang, Chang-xiong, Cui, Han, Liu, Miao, Zhang, Bang-le, Mei, Qi-bing, Lu, Zi-fan, Zhou, Si-yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Mitochondria-targeted Mitochondrial reactive oxygen species Myocardial ischemia/reperfusion injury Precise treatment Resveratrol
Online-Zugang:	Volltext
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