An interdisciplinary review of the thanatomicrobiome in human decomposition
Death does not occur instantaneously and organs do not decompose at the same rate or in the same way. Nulligravid human uteri and prostate glands are the last internal organs to deteriorate during decomposition; however, the reason for this very important observation is still enigmatic. Recent studi...
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| Veröffentlicht in: | Forensic science, medicine, and pathology medicine, and pathology, 2019-03, Vol.15 (1), p.75-83 |
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| container_title | Forensic science, medicine, and pathology |
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| creator | Javan, Gulnaz T. Finley, Sheree J. Tuomisto, Sari Hall, Ashley Benbow, M. Eric Mills, DeEtta |
| description | Death does not occur instantaneously and organs do not decompose at the same rate or in the same way. Nulligravid human uteri and prostate glands are the last internal organs to deteriorate during decomposition; however, the reason for this very important observation is still enigmatic. Recent studies have elucidated that the composition and abundance of microbes in the human thanatomicrobiome (microbiome of death) varies by organ and changes as a function of time and temperature. The ileocecal area has the largest absolute postmortem burden that spreads to the liver and spleen and continues to the heart and brain depending on the cause of death. To truly understand the mechanisms of microbial assembly during decomposition, a thorough examination of different strategies utilized by the trillions of microbes that colonize decaying tissues is needed from a multi-organ and multidisciplinary approach. In this review, we highlight interdisciplinary research and provide an overview of human decomposition investigations of thanatomicrobiomic changes in internal organs. |
| doi_str_mv | 10.1007/s12024-018-0061-0 |
| format | Article |
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Eric</creatorcontrib><creatorcontrib>Mills, DeEtta</creatorcontrib><title>An interdisciplinary review of the thanatomicrobiome in human decomposition</title><title>Forensic science, medicine, and pathology</title><addtitle>Forensic Sci Med Pathol</addtitle><addtitle>Forensic Sci Med Pathol</addtitle><description>Death does not occur instantaneously and organs do not decompose at the same rate or in the same way. Nulligravid human uteri and prostate glands are the last internal organs to deteriorate during decomposition; however, the reason for this very important observation is still enigmatic. Recent studies have elucidated that the composition and abundance of microbes in the human thanatomicrobiome (microbiome of death) varies by organ and changes as a function of time and temperature. The ileocecal area has the largest absolute postmortem burden that spreads to the liver and spleen and continues to the heart and brain depending on the cause of death. To truly understand the mechanisms of microbial assembly during decomposition, a thorough examination of different strategies utilized by the trillions of microbes that colonize decaying tissues is needed from a multi-organ and multidisciplinary approach. 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Eric ; Mills, DeEtta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-9dff31294b198ec2e58ca8ab8ac85224e8915c0aa9b32656afd72aa4073ca0fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Bacterial Physiological Phenomena</topic><topic>Bacterial Translocation</topic><topic>Brain - microbiology</topic><topic>Brain - pathology</topic><topic>Criminology and Criminal Justice</topic><topic>Female</topic><topic>Forensic Medicine</topic><topic>Forensic Pathology</topic><topic>Heart - microbiology</topic><topic>Humans</topic><topic>Liver</topic><topic>Liver - microbiology</topic><topic>Liver - pathology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Microbiota</topic><topic>Myocardium - pathology</topic><topic>Pathology</topic><topic>Postmortem Changes</topic><topic>Prostate - microbiology</topic><topic>Prostate - pathology</topic><topic>Review</topic><topic>Spleen - microbiology</topic><topic>Spleen - pathology</topic><topic>Uterus - microbiology</topic><topic>Uterus - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Javan, Gulnaz T.</creatorcontrib><creatorcontrib>Finley, Sheree J.</creatorcontrib><creatorcontrib>Tuomisto, Sari</creatorcontrib><creatorcontrib>Hall, Ashley</creatorcontrib><creatorcontrib>Benbow, M. 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| subjects | Bacterial Physiological Phenomena Bacterial Translocation Brain - microbiology Brain - pathology Criminology and Criminal Justice Female Forensic Medicine Forensic Pathology Heart - microbiology Humans Liver Liver - microbiology Liver - pathology Male Medicine Medicine & Public Health Microbiota Myocardium - pathology Pathology Postmortem Changes Prostate - microbiology Prostate - pathology Review Spleen - microbiology Spleen - pathology Uterus - microbiology Uterus - pathology |
| title | An interdisciplinary review of the thanatomicrobiome in human decomposition |
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