Identification of a novel KLC1–ROS1 fusion in a case of pediatric low-grade localized glioma

The proto-oncogene tyrosine-protein kinase ROS1 (ROS1) is a tyrosine kinase that is closely related to anaplastic lymphoma kinase receptor (ALK). We describe a novel KLC1–ROS1 fusion identified in a case of pediatric low-grade glioma. This was detected by RNA sequencing and confirmed by reverse-tran...

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Veröffentlicht in:	Brain tumor pathology 2019-01, Vol.36 (1), p.14-19
Hauptverfasser:	Nakano, Yoshiko, Tomiyama, Arata, Kohno, Takashi, Yoshida, Akihiko, Yamasaki, Kai, Ozawa, Tatsuya, Fukuoka, Kohei, Fukushima, Hiroko, Inoue, Takeshi, Hara, Junichi, Sakamoto, Hiroaki, Ichimura, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain cancer Cancer Research Case Report Chemotherapy Glioma Kinases Lung cancer Magnetic resonance imaging Medicine Medicine & Public Health Neurology Neurosurgery Oncology Pathology Pediatrics Proteins Tomography Tumors
Online-Zugang:	Volltext
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