Intestinal organoids: A new paradigm for engineering intestinal epithelium in vitro

In recent years, the advent of intestinal organoid culture systems has revolutionized in vitro studies of the small intestine epithelium. Intestinal organoids are derived from self-organizing and self-renewing intestinal stem cells and closely recapitulate the native intestinal epithelium. They ther...

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Veröffentlicht in:	Biomaterials 2019-02, Vol.194, p.195-214
Hauptverfasser:	Rahmani, Sara, Breyner, Natalia M., Su, Hsuan-Ming, Verdu, Elena F., Didar, Tohid F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Coculture Techniques - instrumentation Coculture Techniques - methods Decellularized small intestine Host-microbial interaction Humans Induced pluripotent stem cells Intestinal Mucosa - cytology Intestines - cytology Organoids Organoids - cytology Organs-on-a-Chips Stem Cells - cytology Tissue engineering Tissue Engineering - instrumentation Tissue Engineering - methods
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